Prof Steve Wolf


Prof Steve Wolf



Steve Wolf received his PT training at Columbia University and then got MS degrees in Physical Therapy (Boston University) and Anatomy (Emory University) followed by his Ph.D. in neurophysiology (Emory University) and post-doctoral work as a Muscular Dystrophy Association of America Fellow (Karolinska Institute, Stockholm). He has been on the faculty at Emory University for almost 40 years since that time where he now is Professor, Departments of Rehabilitation Medicine and Medicine and Associate Professor, Department of Cell Biology. He explore novel interventions to improve extremity use in patients with stroke as well as mechanisms of cortical reorganization and inter-joint coordination associated with such changes. Within the past 23 years he has led several NIH funded clinical trials governing this concept. More recently, his lab has been emphasizing clinical measures of neural plasticity for interventions designed to improve posture in older adults or stroke survivors as well as to improve limb function in the latter group through the addition of electrophysiological (including TMS) and imaging studies. Our newest studies involve use of robotics and mixed reality, both of which have telerehabilitation capabilities and are directed toward home-based treatment post-stroke. Our recently completed NINDS ICARE Trial explored a novel intervention for upper extremity recovery in acute stroke survivors.

Recently our stroke studies have also included obtaining buccal swaps to identify a polymorphism for brain derived nerve growth factor so that we can determine if a relationship exists between the presence of the polymorphism and limitations in reacquisition of motor function. We also study changes in upper extremity movement following stroke using home base robotic and telerehabilitation interfaces that complement our mixed reality studies. While our studies with stroke survivors have addressed primarily efforts to improve motoric function within the upper extremity, we have also done extensive work in monitoring lower extremity muscle activity to determine the extent to which selective feedback can enhance ambulation amongst stroke survivors. In January 2014 he was asked to serve as co-chairman of the Recovery/Rehabilitation Working Group of the newly NINDS funded Stroke Network in which we are one of 25 sites. This honor provides further opportunity to facilitate recruitment and retention strategies for clinical trials. Most recently we have been funded to participate in a multisite trial (NIH U01 NS091951) on use of telerehabilitation to facilitate upper extremity functional return within 90 days after stroke.  This study, led by Steven Cramer, MD, is the first rehabilitation and recovery project funded through the Stroke Network. This work is compatible with our experiences in a successful, home-based robotics study (RC3 NS070646-01) recently completed in collaboration with colleagues at the Cleveland Clinic that targeted chronic stroke survivors. We have recently completed a 4 year project in which 24 clinicians and scientists volunteered their time to create an evidence based algorithm to instruct clinicians regarding best practice for treatment of upper extremities following stroke

All session by Prof Steve Wolf

  • Flemming17-Mar-2016

Collaborative decision making and development of best evidence apps